About

A Transformational Platform

What Differentiates Us?

Pike’s proprietary continuous delivery technology is designed to increase tolerability, reduce toxicity and target superior patient outcomes over a 7-day period.

What Does This Mean?

Our platform reduces the area under the curve (AUC) and maximum plasma concentration (Cmax) and targets a continuous therapeutic effect while avoiding periods of subtherapeutic dosing. We are able to offer significantly less drug exposure compared to oral administration which increases tolerability, decreases toxicity, and significantly reduces adverse events and negative side effects.

In addition, with a 7-day therapy, we will avoid daily oral multi-dosing for increased convenience and compliance.

Leading with Parkinson’s Disease

There are 1 million people suffering with Parkinson’s in the U.S., and approximately 10 million suffering globally.  Parkinson’s is a complex chronic, progressive, neurodegenerative disease with no cure. It continues to have a myriad of significant unmet needs, and patients suffer from – motor symptoms like tremor, dyskinesia, bradykinesia, dystonia, postural instability to name a few, but also non-motor symptoms like anxiety, depression, sleep disorders, pain and psychosis.

Non-motor symptoms can often be more detrimental to patients’ overall well-being and quality of life. These non-motor symptoms can be related to Parkinson’s itself, or from the medications used to treat it. For non-motor symptom management, pharmacotherapy selection can be based on considerations of safety and tolerability, and none of the drugs have shown clear difference in controlling non-motor symptoms in Parkinson’s Disease specific populations.

To address patient’s needs, Pike is developing proprietary transdermal CBD technology that can provide continuous treatment delivery over a 7 day period. This would be the first Parkinson’s specific therapy targeted to treat multiple non-motor symptoms and motor symptoms. 

Pike’s Unique Development Advantage

Pike has an exclusive partnership with Transdermal Research Pharm Laboratories LLC (TRPL). TRPL has over 70 years’ experience in developing sophisticated delivery systems and formulation, and is also registered and approved by the DEA, FDA, and the State of NY to research and develop treatments using controlled substances.

Pike Therapeutics Inc. is a spin out of Starton Therapeutics Inc.